A Computational Approach to Edge Detection
IEEE Transactions on Pattern Analysis and Machine Intelligence
Scale-Space and Edge Detection Using Anisotropic Diffusion
IEEE Transactions on Pattern Analysis and Machine Intelligence
Fast Approximate Energy Minimization via Graph Cuts
IEEE Transactions on Pattern Analysis and Machine Intelligence
Mean Shift: A Robust Approach Toward Feature Space Analysis
IEEE Transactions on Pattern Analysis and Machine Intelligence
Estimation with Applications to Tracking and Navigation
Estimation with Applications to Tracking and Navigation
Bilateral Filtering for Gray and Color Images
ICCV '98 Proceedings of the Sixth International Conference on Computer Vision
An Experimental Comparison of Min-Cut/Max-Flow Algorithms for Energy Minimization in Vision
IEEE Transactions on Pattern Analysis and Machine Intelligence
Image Analysis, Random Fields and Markov Chain Monte Carlo Methods: A Mathematical Introduction (Stochastic Modelling and Applied Probability)
Bayesian tracking of elongated structures in 3D images
IPMI'07 Proceedings of the 20th international conference on Information processing in medical imaging
Bayesian tracking of tubular structures and its application to carotid arteries in CTA
MICCAI'07 Proceedings of the 10th international conference on Medical image computing and computer-assisted intervention
Microscope Image Processing
A tutorial on particle filters for online nonlinear/non-GaussianBayesian tracking
IEEE Transactions on Signal Processing
IEEE Transactions on Image Processing
IEEE Transactions on Image Processing
IEEE Transactions on Image Processing
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Studying intracellular dynamics is of fundamental importance for understanding healthy life at the molecular level and for developing drugs to target disease processes. One of the key technologies to enable this research is the automated tracking and motion analysis of these objects in microscopy image sequences. To make better use of the spatiotemporal information than common frame-by-frame tracking methods, two alternative approaches have recently been proposed, based upon either Bayesian estimation or space-time segmentation. In this paper, we propose to combine the power of both approaches, and develop a new probabilistic method to segment the traces of the moving objects in kymograph representations of the image data. It is based on variable-rate particle filtering and uses multiscale trend analysis of the extracted traces to estimate the relevant kinematic parameters. Experiments on realistic synthetically generated images as well as on real biological image data demonstrate the improved potential of the new method for the analysis of microtubule dynamics in vitro.