Dissociating Reading Processes on the Basis of Neuronal Interactions
Journal of Cognitive Neuroscience
Neural Correlates of Letter-String Length and Lexicality during Reading in a Regular Orthography
Journal of Cognitive Neuroscience
Neuroimaging Studies of Word and Pseudoword Reading: Consistencies, Inconsistencies, and Limitations
Journal of Cognitive Neuroscience
The Effects of Presentation Rate During Word and Pseudoword Reading: A Comparison of PET and fMRI
Journal of Cognitive Neuroscience
Conceptual Processing during the Conscious Resting State: A Functional MRI Study
Journal of Cognitive Neuroscience
Taxi vs. Taksi: On Orthographic Word Recognition in the Left Ventral Occipitotemporal Cortex
Journal of Cognitive Neuroscience
Common blood flow changes across visual tasks: Ii. decreases in cerebral cortex
Journal of Cognitive Neuroscience
On the functional neuroanatomy of visual word processing: Effects of case and letter deviance
Journal of Cognitive Neuroscience
Hi-index | 0.00 |
In a previous study of single word reading, regions in the left supramarginal gyrus and left angular gyrus showed positive BOLD activity in children but significantly less activity in adults for high-frequency words [Church, J. A., Coalson, R. S., Lugar, H. M., Petersen, S. E., & Schlaggar, B. L. A developmental fMRI study of reading and repetition reveals changes in phonological and visual mechanisms over age. Cerebral Cortex, 18, 2054-2065, 2008]. This developmental decrease may reflect decreased reliance on phonological processing for familiar stimuli in adults. Therefore, in the present study, variables thought to influence phonological demand (string length and lexicality) were manipulated. Length and lexicality effects in the brain were explored using both ROI and whole-brain approaches. In the ROI analysis, the supramarginal and angular regions from the previous study were applied to this study. The supramarginal region showed a significant positive effect of length, consistent with a role in phonological processing, whereas the angular region showed only negative deflections from baseline with a strong effect of lexicality and other weaker effects. At the whole-brain level, varying effects of length and lexicality and their interactions were observed in 85 regions throughout the brain. The application of hierarchical clustering analysis to the BOLD time course data derived from these regions revealed seven clusters, with potentially revealing anatomical locations. Of note, a left angular gyrus region was the sole constituent of one cluster. Taken together, these findings in adult readers (1) provide support for a widespread set of brain regions affected by lexical variables, (2) corroborate a role for phonological processing in the left supramarginal gyrus, and (3) do not support a strong role for phonological processing in the left angular gyrus.