Ontological foundation for protein data models

Authors:
Amandeep S. Sidhu;Tharam S. Dillon;Elizabeth Chang
Affiliations:
Faculty of Information Technology, University of Technology, Sydney, Australia;Faculty of Information Technology, University of Technology, Sydney, Australia;School of Information Systems, Curtin University of Technical University, Perth, Australia
Venue:
OTM'05 Proceedings of the 2005 OTM Confederated international conference on On the Move to Meaningful Internet Systems
Year:
2005

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Abstract

In this paper we proposed a Protein Ontology to integrate protein data and information from various Protein Data Sources. Protein Ontology provides the technical and scientific infrastructure and knowledge to allow description and analysis of relationships between various proteins. Protein Ontology uses relevant protein data sources of information like PDB, SCOP, and OMIM. Protein Ontology describes: Protein Sequence and Structure Information, Protein Folding Process, Cellular Functions of Proteins, Molecular Bindings internal and external to Proteins, and Constraints affecting the Final Protein Conformation. We also created a database of 10 Major Prion Proteins available in various Protein data sources, based on the vocabulary provided by Protein Ontology. Details about Protein Ontology are available online at http://www.proteinontology.info/.