Efficiently Mining Frequent Trees in a Forest: Algorithms and Applications
IEEE Transactions on Knowledge and Data Engineering
De novo identification of repeat families in large genomes
Bioinformatics
Spatial representation of symbolic sequences through iterative function systems
IEEE Transactions on Systems, Man, and Cybernetics, Part A: Systems and Humans
Computationally efficient matching of microRNA shapes using mutual symmetry
SIP '07 Proceedings of the Ninth IASTED International Conference on Signal and Image Processing
On the Local Form and Transitions of Pre-symmetry Sets
Journal of Mathematical Imaging and Vision
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Two promising approaches for handling large-scale biodata are presented and illustrated in several new contexts: molecular structure bitmap image processing for chemoinformatics, and fractal visualization methods for genome analyses. It is suggested that two-dimensional structure databases of bioactive molecules (e.g. proteins, drugs, folded RNAs), transformed to bitmap image databases, can be analysed by a variety of image processing methods, with an example of human microRNA folded 2D structures processed by Gabor filter. Another compact and efficient visualization method is comparison of huge amounts of genomic and proteomic data through fractal representation, with an example of analyzing oligomer frequencies in a bacterial phytoplasma genome. Bitmap visualization of bioinformatics data seems promising for complex parallel pattern discovery and large-scale genome comparisons, as powerful modern image processing methods can be applied to the 2D images.