The nature of statistical learning theory
The nature of statistical learning theory
Least Squares Support Vector Machine Classifiers
Neural Processing Letters
An introduction to support Vector Machines: and other kernel-based learning methods
An introduction to support Vector Machines: and other kernel-based learning methods
Bayesian Learning for Neural Networks
Bayesian Learning for Neural Networks
Neural Networks for Pattern Recognition
Neural Networks for Pattern Recognition
The Case against Accuracy Estimation for Comparing Induction Algorithms
ICML '98 Proceedings of the Fifteenth International Conference on Machine Learning
Bayesian Networks in Ovarian Cancer Diagnosis: Potentials and Limitations
CBMS '00 Proceedings of the 13th IEEE Symposium on Computer-Based Medical Systems (CBMS'00)
The evidence framework applied to classification networks
Neural Computation
Artificial Intelligence in Medicine
IEEE Transactions on Neural Networks
The use of receiver operating characteristic curves in biomedical informatics
Journal of Biomedical Informatics - Special issue: Clinical machine learning
Cellular automata for simulating land use changes based on support vector machines
Computers & Geosciences
Multi-class support vector machine for classification of the ultrasonic images of supraspinatus
Expert Systems with Applications: An International Journal
Artificial Intelligence in Medicine
Advanced soft computing diagnosis method for tumour grading
Artificial Intelligence in Medicine
Proceedings of the 2009 conference on Computational Intelligence and Bioengineering: Essays in Memory of Antonina Starita
Expert Systems with Applications: An International Journal
ICANN'07 Proceedings of the 17th international conference on Artificial neural networks
An optimal method for prediction and adjustment on byproduct gas holder in steel industry
Expert Systems with Applications: An International Journal
Improved modeling of clinical data with kernel methods
Artificial Intelligence in Medicine
Modeling Paradigms for Medical Diagnostic Decision Support: A Survey and Future Directions
Journal of Medical Systems
Classification of EMG signals using PSO optimized SVM for diagnosis of neuromuscular disorders
Computers in Biology and Medicine
Hi-index | 0.00 |
In this work, we develop and evaluate several least squares support vector machine (LS-SVM) classifiers within the Bayesian evidence framework, in order to preoperatively predict malignancy of ovarian tumors. The analysis includes exploratory data analysis, optimal input variable selection, parameter estimation, and performance evaluation via receiver operating characteristic (ROC) curve analysis. LS-SVM models with linear and radial basis function (RBF) kernels, and logistic regression models have been built on 265 training data, and tested on 160 newly collected patient data. The LS-SVM model with nonlinear RBF kernel achieves the best performance, on the test set with the area under the ROC curve (AUC), sensitivity and specificity equal to 0.92, 81.5% and 84.0%, respectively. The best averaged performance over 30 runs of randomized cross-validation is also obtained by an LS-SVM RBF model, with AUC, sensitivity and specificity equal to 0.94, 90.0% and 80.6%, respectively. These results show that the LS-SVM models have the potential to obtain a reliable preoperative distinction between benign and malignant ovarian tumors, and to assist the clinicians for making a correct diagnosis.