Intrinsic protein distribution on manifolds embedded in low-dimensional space

Authors:
Wei-Chen Cheng
Affiliations:
Institute of Statistical Science, Academia Sinica, Republic of China
Venue:
ICSI'12 Proceedings of the Third international conference on Advances in Swarm Intelligence - Volume Part II
Year:
2012

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Abstract

There has been more than twenty thousand proteins in human body been sequenced. This work applies three manifold learning techniques, which preserve distinct relations among proteins coded by human DNA, to explore the geometry of the distribution of genes in three-dimensional space. The simulations suggest that the relations hidden among genetic amino-acid sequences could be explored by the manifolds embedded in Euclidean space.