Identifying well-formed biomedical phrases in MEDLINE® text

  • Authors:
  • Won Kim;Lana Yeganova;Donald C. Comeau;W. John Wilbur

  • Affiliations:
  • National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA;National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA;National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA;National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA

  • Venue:
  • Journal of Biomedical Informatics
  • Year:
  • 2012

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Abstract

In the modern world people frequently interact with retrieval systems to satisfy their information needs. Humanly understandable well-formed phrases represent a crucial interface between humans and the web, and the ability to index and search with such phrases is beneficial for human-web interactions. In this paper we consider the problem of identifying humanly understandable, well formed, and high quality biomedical phrases in MEDLINE documents. The main approaches used previously for detecting such phrases are syntactic, statistical, and a hybrid approach combining these two. In this paper we propose a supervised learning approach for identifying high quality phrases. First we obtain a set of known well-formed useful phrases from an existing source and label these phrases as positive. We then extract from MEDLINE a large set of multiword strings that do not contain stop words or punctuation. We believe this unlabeled set contains many well-formed phrases. Our goal is to identify these additional high quality phrases. We examine various feature combinations and several machine learning strategies designed to solve this problem. A proper choice of machine learning methods and features identifies in the large collection strings that are likely to be high quality phrases. We evaluate our approach by making human judgments on multiword strings extracted from MEDLINE using our methods. We find that over 85% of such extracted phrase candidates are humanly judged to be of high quality.