Biocomputation: modeling and analyzing biomolecular networks

  • Authors:
  • Rajeev Alur;Calin Belta;Vijay Kumar;Max Mintz;George J. Pappas;Harvey Rubin;Jonathan Schug

  • Affiliations:
  • University of Pennsylvania;University of Pennsylvania;University of Pennsylvania;University of Pennsylvania;University of Pennsylvania;University of Pennsylvania;University of Pennsylvania

  • Venue:
  • Computing in Science and Engineering
  • Year:
  • 2002

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Abstract

The authors argue for the need to model and analyze biological networks at molecular and cellular levels. They propose a computational toolbox for biologists. Central to their approach is the paradigm of hybrid models in which discrete events are combined with continuous differential equations to capture switching behavior.