Reconciliation problems for duplication, loss and horizontal gene transfer

  • Authors:
  • Pawel Górecki

  • Affiliations:
  • Warsaw University, Warsaw, Poland

  • Venue:
  • RECOMB '04 Proceedings of the eighth annual international conference on Resaerch in computational molecular biology
  • Year:
  • 2004

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Abstract

This paper presents a model of reconciling a species tree and a gene tree in an extended duplication-loss model. In the first part the definition of a model is introduced. In the second the horizontal transfer is defined and a new polynomial reconciliation algorithm is presented. We prove NP-completeness of the important problem related to the reconstruction of the species relationships with transfers from a given set of gene family trees. Some new problems are stated. We present a simple biological example.