User-Centered Design: An Integrated Approach with Cdrom
User-Centered Design: An Integrated Approach with Cdrom
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EDOC '02 Proceedings of the 6th International Enterprise Distributed Object Computing Conference
Data integration through database federation
IBM Systems Journal
Business artifacts: An approach to operational specification
IBM Systems Journal
Integrated model-driven dashboard development
Information Systems Frontiers
Artifact-centered operational modeling: lessons from customer engagements
IBM Systems Journal
Specification and Verification of Artifact Behaviors in Business Process Models
ICSOC '07 Proceedings of the 5th international conference on Service-Oriented Computing
On the Duality of Information-Centric and Activity-Centric Models of Business Processes
CAiSE '08 Proceedings of the 20th international conference on Advanced Information Systems Engineering
Predicting Coupling of Object-Centric Business Process Implementations
BPM '08 Proceedings of the 6th International Conference on Business Process Management
Artifact-Centric Business Process Models: Brief Survey of Research Results and Challenges
OTM '08 Proceedings of the OTM 2008 Confederated International Conferences, CoopIS, DOA, GADA, IS, and ODBASE 2008. Part II on On the Move to Meaningful Internet Systems
Automatic construction of simple artifact-based business processes
Proceedings of the 12th International Conference on Database Theory
Automatic verification of data-centric business processes
Proceedings of the 12th International Conference on Database Theory
Reflection of a Year Long Model-Driven Business and UI Modeling Development Project
INTERACT '09 Proceedings of the 12th IFIP TC 13 International Conference on Human-Computer Interaction: Part II
Facilitating Workflow Interoperation Using Artifact-Centric Hubs
ICSOC-ServiceWave '09 Proceedings of the 7th International Joint Conference on Service-Oriented Computing
Artifact-Centric Workflow Dominance
ICSOC-ServiceWave '09 Proceedings of the 7th International Joint Conference on Service-Oriented Computing
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CAiSE'07 Proceedings of the 19th international conference on Advanced information systems engineering
A multi-view model-driven approach for packaging software components
Proceedings of the 2010 ACM Symposium on Applied Computing
Towards a theory of web service choreographies
WS-FM'07 Proceedings of the 4th international conference on Web services and formal methods
Towards formal analysis of artifact-centric business process models
BPM'07 Proceedings of the 5th international conference on Business process management
Automated realization of business workflow specification
ICSOC/ServiceWave'09 Proceedings of the 2009 international conference on Service-oriented computing
Artifact systems with data dependencies and arithmetic
Proceedings of the 14th International Conference on Database Theory
Automatic verification of data-centric business processes
BPM'11 Proceedings of the 9th international conference on Business process management
Foundations of relational artifacts verification
BPM'11 Proceedings of the 9th international conference on Business process management
Artifact systems with data dependencies and arithmetic
ACM Transactions on Database Systems (TODS)
Journal of Database Management
Recognizing Valid Artifacts in Business Processes
WI-IAT '12 Proceedings of the The 2012 IEEE/WIC/ACM International Joint Conferences on Web Intelligence and Intelligent Agent Technology - Volume 03
Foundations of data-aware process analysis: a database theory perspective
Proceedings of the 32nd symposium on Principles of database systems
Data management perspectives on business process management: tutorial overview
Proceedings of the 2013 ACM SIGMOD International Conference on Management of Data
Representations of Artifact-Centric Business Processes
International Journal of Productivity Management and Assessment Technologies
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Despite year-to-year increases in R & D budgets, the number of successful NCEs (new chemical entities) has continued to decline. Drug companies are looking into new ways to make research processes more efficient, to manage information better, and to improve collaboration among research groups. This shift from an artisan approach to an organized, streamlined discovery process is often termed the "industrialization of discovery processes." This paper presents an approach to industrializing drug discovery that involves the formal modeling of research processes at several layers of abstraction, mappings between adjacent layers, and an implementation of this hierarchy using information technology-level execution elements. This approach is applied to the assay development phase of the drug discovery process. First, a business operations model is built by identifying the business artifacts, developing models for the life cycles of these artifacts, and then creating a comprehensive model that combines these life-cycle models and their interactions. Using the concept of adaptive business objects, a solution composition model that expands on the business operations model is developed. This model is then mapped into an executable platform-specific implementation by using the IBM WebSphere® platform. Our prototype system was built and validated as a joint effort between IBM Research and Bayer HealthCare.