Successive State Transitions with I/O Interface by Molecules

  • Authors:
  • Ken Komiya;Kensaku Sakamoto;Hidetaka Gouzu;Shigeyuki Yokoyama;Masanori Arita;Akio Nishikawa;Masami Hagiya

  • Affiliations:
  • -;-;-;-;-;-;-

  • Venue:
  • DNA '00 Revised Papers from the 6th International Workshop on DNA-Based Computers: DNA Computing
  • Year:
  • 2000

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Abstract

This paper reports three experimental achievements in our computation model based on 'whiplash' reactions. We first show that a single-stranded DNA (ssDNA) can serve as an independent machine by using a solid support technique. Second, we show how to append an arbitrary sequence, e.g. a transition state or a PCR primer, to the 3'- end of a molecular machine, thus realizing its I/O interface. Finally we demonstrate the successive state transitions for several steps on solid phase with I/O.