Multi-way relation classification: application to protein-protein interactions

  • Authors:
  • Barbara Rosario;Marti A. Hearst

  • Affiliations:
  • UC Berkeley, Berkeley, CA;UC Berkeley, Berkeley, CA

  • Venue:
  • HLT '05 Proceedings of the conference on Human Language Technology and Empirical Methods in Natural Language Processing
  • Year:
  • 2005

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Abstract

We address the problem of multi-way relation classification, applied to identification of the interactions between proteins in bioscience text. A major impediment to such work is the acquisition of appropriately labeled training data; for our experiments we have identified a database that serves as a proxy for training data. We use two graphical models and a neural net for the classification of the interactions, achieving an accuracy of 64% for a 10-way distinction between relation types. We also provide evidence that the exploitation of the sentences surrounding a citation to a paper can yield higher accuracy than other sentences.