VISI Physical Design Automation: Theory and Practice
VISI Physical Design Automation: Theory and Practice
The equivalence of theorem proving and the interconnection problem
ACM SIGDA Newsletter
Unified high-level synthesis and module placement for defect-tolerant microfluidic biochips
Proceedings of the 42nd annual Design Automation Conference
Droplet routing in the synthesis of digital microfluidic biochips
Proceedings of the conference on Design, automation and test in Europe: Proceedings
Priority scheduling in digital microfluidics-based biochips
Proceedings of the conference on Design, automation and test in Europe: Proceedings
Chemical and Biological Applications of Digital-Microfluidic Devices
IEEE Design & Test
Integrated droplet routing in the synthesis of microfluidic biochips
Proceedings of the 44th annual Design Automation Conference
High-level synthesis of digital microfluidic biochips
ACM Journal on Emerging Technologies in Computing Systems (JETC)
BioRoute: a network-flow based routing algorithm for digital microfluidic biochips
Proceedings of the 2007 IEEE/ACM international conference on Computer-aided design
A high-performance droplet router for digital microfluidic biochips
Proceedings of the 2008 international symposium on Physical design
Modeling and Controlling Parallel Tasks in Droplet-Based Microfluidic Systems
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Tabu search-based synthesis of dynamically reconfigurable digital microfluidic biochips
CASES '09 Proceedings of the 2009 international conference on Compilers, architecture, and synthesis for embedded systems
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Design automation and test solutions for digital microfluidic biochips
IEEE Transactions on Circuits and Systems Part I: Regular Papers
Proceedings of the 47th Design Automation Conference
Cross-contamination aware design methodology for pin-constrained digital microfluidic biochips
Proceedings of the 47th Design Automation Conference
ILP-based pin-count aware design methodology for microfluidic biochips
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
A contamination aware droplet routing algorithm for the synthesis of digital microfluidic biochips
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Fast high-performance algorithms for multi-pin droplet routing in digital microfluidic biochips
Proceedings of the 21st edition of the great lakes symposium on Great lakes symposium on VLSI
On residue removal in digital microfluidic biochips
Proceedings of the 21st edition of the great lakes symposium on Great lakes symposium on VLSI
Digital microfluidic biochips: recent research and emerging challenges
CODES+ISSS '11 Proceedings of the seventh IEEE/ACM/IFIP international conference on Hardware/software codesign and system synthesis
Digital microfluidic biochips: a vision for functional diversity and more than Moore
Proceedings of the International Conference on Computer-Aided Design
Integration, the VLSI Journal
Proceedings of the eighth IEEE/ACM/IFIP international conference on Hardware/software codesign and system synthesis
Optimization algorithms for the design of digital microfluidic biochips: A survey
Computers and Electrical Engineering
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Recent advances in droplet-based digital microfluidics have enabled biochip devices for DNA sequencing, immunoassays, clinical chemistry, and protein crystallization. Since cross-contamination between droplets of different biomolecules can lead to erroneous outcomes for bioassays, the avoidance of cross-contamination during droplet routing is a key design challenge for biochips. We propose a droplet-routing method that avoids cross-contamination in the optimization of droplet flow paths. The proposed approach targets disjoint droplet routes and minimizes the number of cells used for droplet routing. We also minimize the number of wash operations that must be used between successive routing steps that share unit cells in the microfluidic array. Two real-life biochemical applications are used to evaluate the proposed droplet-routing methods.