A front-tracking method for viscous, incompressible, multi-fluid flows
Journal of Computational Physics
Unified high-level synthesis and module placement for defect-tolerant microfluidic biochips
Proceedings of the 42nd annual Design Automation Conference
Architectural-level synthesis of digital microfluidics-based biochips
Proceedings of the 2004 IEEE/ACM International conference on Computer-aided design
Droplet routing in the synthesis of digital microfluidic biochips
Proceedings of the conference on Design, automation and test in Europe: Proceedings
Test Planning and Test Resource Optimization for Droplet-Based Microfluidic Systems
Journal of Electronic Testing: Theory and Applications
Module placement for fault-tolerant microfluidics-based biochips
Proceedings of the 41st annual Design Automation Conference
CODES+ISSS '06 Proceedings of the 4th international conference on Hardware/software codesign and system synthesis
Testing and Diagnosis of Realistic Defects in Digital Microfluidic Biochips
Journal of Electronic Testing: Theory and Applications
Placement of defect-tolerant digital microfluidic biochips using the T-tree formulation
ACM Journal on Emerging Technologies in Computing Systems (JETC)
Broadcast electrode-addressing for pin-constrained multi-functional digital microfluidic biochips
Proceedings of the 45th annual Design Automation Conference
Tabu search-based synthesis of dynamically reconfigurable digital microfluidic biochips
CASES '09 Proceedings of the 2009 international conference on Compilers, architecture, and synthesis for embedded systems
A two-stage ILP-based droplet routing algorithm for pin-constrained digital microfluidic biochips
Proceedings of the 19th international symposium on Physical design
ACM Journal on Emerging Technologies in Computing Systems (JETC)
ICCD'09 Proceedings of the 2009 IEEE international conference on Computer design
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Proceedings of the 47th Design Automation Conference
Cross-contamination aware design methodology for pin-constrained digital microfluidic biochips
Proceedings of the 47th Design Automation Conference
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
ILP-based pin-count aware design methodology for microfluidic biochips
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Cross-contamination avoidance for droplet routing in digital microfluidic biochips
Proceedings of the Conference on Design, Automation and Test in Europe
A network-flow based pin-count aware routing algorithm for broadcast electrode-addressing EWOD chips
Proceedings of the International Conference on Computer-Aided Design
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Modeling and Controlling Parallel Tasks in Droplet-Based Microfluidic Systems
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
A High-Performance Droplet Routing Algorithm for Digital Microfluidic Biochips
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
BioRoute: A Network-Flow-Based Routing Algorithm for the Synthesis of Digital Microfluidic Biochips
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Proceedings of the 48th Design Automation Conference
Digital microfluidic biochips: recent research and emerging challenges
CODES+ISSS '11 Proceedings of the seventh IEEE/ACM/IFIP international conference on Hardware/software codesign and system synthesis
Proceedings of the International Conference on Computer-Aided Design
Integrated fluidic-chip co-design methodology for digital microfluidic biochips
Proceedings of the 2012 ACM international symposium on International Symposium on Physical Design
Voltage-aware chip-level design for reliability-driven pin-constrained EWOD chips
Proceedings of the International Conference on Computer-Aided Design
Proceedings of the International Conference on Computer-Aided Design
Reliability-driven chip-level design for high-frequency digital microfluidic biochips
Proceedings of the 2014 on International symposium on physical design
Sample preparation for many-reactant bioassay on DMFBs using common dilution operation sharing
Proceedings of the International Conference on Computer-Aided Design
| Hi-index | 0.00 |
Advances in droplet-based digital microfluidics have led to the emergence of biochips for automating laboratory procedures in biochemistry and molecular biology. These devices enable the precise control of microliter of nanoliter volumes of biochemical samples and reagents. They combine electronics with biology, and integrate various bioassay operations, such as sample preparation, analysis, separation, and detection. Compared to conventional laboratory procedures, which are cumbersome and expensive, miniaturized digital microfluidic biochips (DMFBs) offer the advantages of higher sensitivity, lower cost, system integration, and less likelihood of human error. This tutorial paper provides an overview of DMFBs and describes emerging computer-aided design (CAD) tools for the automated synthesis and optimization of biochips, from physical modeling to fluidic-level synthesis and then to chip-level design. By efficiently utilizing the electronic design automation (EDA) technique on emerging CAD tools, users can concentrate on the development of nanoscale bioassays, leaving chip optimization and implementation details to design-automation tools.