Graph theory and its applications
Graph theory and its applications
Introduction to Algorithms
Priority scheduling in digital microfluidics-based biochips
Proceedings of the conference on Design, automation and test in Europe: Proceedings
CODES+ISSS '06 Proceedings of the 4th international conference on Hardware/software codesign and system synthesis
Chemical and Biological Applications of Digital-Microfluidic Devices
IEEE Design & Test
Proceedings of the conference on Design, automation and test in Europe
BioRoute: a network-flow based routing algorithm for digital microfluidic biochips
Proceedings of the 2007 IEEE/ACM international conference on Computer-aided design
Modeling and Controlling Parallel Tasks in Droplet-Based Microfluidic Systems
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
ILP-based pin-count aware design methodology for microfluidic biochips
Proceedings of the 46th Annual Design Automation Conference
A two-stage ILP-based droplet routing algorithm for pin-constrained digital microfluidic biochips
Proceedings of the 19th international symposium on Physical design
Design automation and test solutions for digital microfluidic biochips
IEEE Transactions on Circuits and Systems Part I: Regular Papers
Cross-contamination aware design methodology for pin-constrained digital microfluidic biochips
Proceedings of the 47th Design Automation Conference
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
ILP-based pin-count aware design methodology for microfluidic biochips
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Co-optimization of droplet routing and pin assignment in disposable digital microfluidic biochips
Proceedings of the 2011 international symposium on Physical design
Fault Diagnosis in Lab-on-Chip Using Digital Microfluidic Logic Gates
Journal of Electronic Testing: Theory and Applications
Proceedings of the 48th Design Automation Conference
Digital microfluidic biochips: recent research and emerging challenges
CODES+ISSS '11 Proceedings of the seventh IEEE/ACM/IFIP international conference on Hardware/software codesign and system synthesis
Proceedings of the International Conference on Computer-Aided Design
A network-flow based pin-count aware routing algorithm for broadcast electrode-addressing EWOD chips
Proceedings of the International Conference on Computer-Aided Design
Digital microfluidic biochips: a vision for functional diversity and more than Moore
Proceedings of the International Conference on Computer-Aided Design
Integrated fluidic-chip co-design methodology for digital microfluidic biochips
Proceedings of the 2012 ACM international symposium on International Symposium on Physical Design
Integration, the VLSI Journal
Design of pin-constrained general-purpose digital microfluidic biochips
Proceedings of the 49th Annual Design Automation Conference
Congestion-aware layout design for high-throughput digital microfluidic biochips
ACM Journal on Emerging Technologies in Computing Systems (JETC)
Fast online synthesis of generally programmable digital microfluidic biochips
Proceedings of the eighth IEEE/ACM/IFIP international conference on Hardware/software codesign and system synthesis
Proceedings of the eighth IEEE/ACM/IFIP international conference on Hardware/software codesign and system synthesis
Voltage-aware chip-level design for reliability-driven pin-constrained EWOD chips
Proceedings of the International Conference on Computer-Aided Design
Dictionary-based error recovery in cyberphysical digital-microfluidic biochips
Proceedings of the International Conference on Computer-Aided Design
Optimization algorithms for the design of digital microfluidic biochips: A survey
Computers and Electrical Engineering
A field-programmable pin-constrained digital microfluidic biochip
Proceedings of the 50th Annual Design Automation Conference
IEEE Transactions on Very Large Scale Integration (VLSI) Systems
Reliability-driven chip-level design for high-frequency digital microfluidic biochips
Proceedings of the 2014 on International symposium on physical design
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Recent advances in digital microfluidics have enabled lab-on-a-chip devices for DNA sequencing, immunoassays, clinical chemistry, and protein crystallization. Basic operations such as droplet dispensing, mixing, dilution, localized heating, and incubation can be carried out using a two-dimensional array of electrodes and nanoliter volumes of liquid. The number of independent input pins used to control the electrodes in such microfluidic "biochips" is an important cost-driver, especially for disposable PCB devices that are being developed for clinical and point-of-care diagnostics. However, most prior work on biochip design-automation has assumed independent control of the electrodes using a large number of input pins. Another limitation of prior work is that the mapping of control pins to electrodes is only applicable for a specific bioassay. We present a broadcast-addressing-based design technique for pin-constrained multi-functional biochips. The proposed method provides high throughput for bioassays and it reduces the number of control pins by identifying and connecting control pins with "compatible" actuation sequences. The proposed method is evaluated using a multifunctional chip designed to execute a set of multiplexed bioassays, the polymerase chain reaction, and a protein dilution assay.