Rectangle-packing-based module placement
ICCAD '95 Proceedings of the 1995 IEEE/ACM international conference on Computer-aided design
RECOMB '97 Proceedings of the first annual international conference on Computational molecular biology
An O-tree representation of non-slicing floorplan and its applications
Proceedings of the 36th annual ACM/IEEE Design Automation Conference
B*-Trees: a new representation for non-slicing floorplans
Proceedings of the 37th Annual Design Automation Conference
FAST-SP: a fast algorithm for block placement based on sequence pair
Proceedings of the 2001 Asia and South Pacific Design Automation Conference
TCG: a transitive closure graph-based representation for non-slicing floorplans
Proceedings of the 38th annual Design Automation Conference
VISI Physical Design Automation: Theory and Practice
VISI Physical Design Automation: Theory and Practice
An Introduction to VLSI Physical Design
An Introduction to VLSI Physical Design
Fast Template Placement for Reconfigurable Computing Systems
IEEE Design & Test
Mining for empty spaces in large data sets
Theoretical Computer Science - Database theory
RSP '99 Proceedings of the Tenth IEEE International Workshop on Rapid System Prototyping
Algorithms for testing that sets of DNA words concatenate without secondary structure
Natural Computing: an international journal
A Fast Algorithm for Finding Maximal Empty Rectangles for Dynamic FPGA Placement
Proceedings of the conference on Design, automation and test in Europe - Volume 1
CAD challenges in BioMEMS design
Proceedings of the 41st annual Design Automation Conference
Temporal floorplanning using 3D-subTCG
Proceedings of the 2004 Asia and South Pacific Design Automation Conference
Technology mapping and architecture evalution for k/m-macrocell-based FPGAs
ACM Transactions on Design Automation of Electronic Systems (TODAES)
Modern floorplanning based on fast simulated annealing
Proceedings of the 2005 international symposium on Physical design
Architectural-level synthesis of digital microfluidics-based biochips
Proceedings of the 2004 IEEE/ACM International conference on Computer-aided design
Temporal floorplanning using the T-tree formulation
Proceedings of the 2004 IEEE/ACM International conference on Computer-aided design
Concurrent Testing of Droplet-Based Microfluidic Systems for Multiplexed Biomedical Assays
ITC '04 Proceedings of the International Test Conference on International Test Conference
An evaluation of parallel simulated annealing strategies with application to standard cell placement
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Fast evaluation of sequence pair in block placement by longest common subsequence computation
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Scheduling of microfluidic operations for reconfigurable two-dimensional electrowetting arrays
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Twin binary sequences: a nonredundant representation for general nonslicing floorplan
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Retiming-based timing analysis with an application to mincut-based global placement
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Mixed block placement via fractional cut recursive bisection
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Algorithms in FastStokes and Its Application to Micromachined Device Simulation
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Computer-Aided Optimization of DNA Array Design and Manufacturing
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Synthesis of Multiplexed Biofluidic Microchips
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Performance Characterization of a Reconfigurable Planar-Array Digital Microfluidic System
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Multiple fault diagnosis in digital microfluidic biochips
ACM Journal on Emerging Technologies in Computing Systems (JETC)
Computer-Aided Design and Test for Digital Microfluidics
IEEE Design & Test
Heterogeneous systems on chip and systems in package
Proceedings of the conference on Design, automation and test in Europe
Integrated droplet routing in the synthesis of microfluidic biochips
Proceedings of the 44th annual Design Automation Conference
ACM Journal on Emerging Technologies in Computing Systems (JETC)
High-level synthesis of digital microfluidic biochips
ACM Journal on Emerging Technologies in Computing Systems (JETC)
A high-performance droplet router for digital microfluidic biochips
Proceedings of the 2008 international symposium on Physical design
Integrated droplet routing and defect tolerance in the synthesis of digital microfluidic biochips
ACM Journal on Emerging Technologies in Computing Systems (JETC)
Efficient parallel testing and diagnosis of digital microfluidic biochips
ACM Journal on Emerging Technologies in Computing Systems (JETC)
Tabu search-based synthesis of dynamically reconfigurable digital microfluidic biochips
CASES '09 Proceedings of the 2009 international conference on Compilers, architecture, and synthesis for embedded systems
Design automation and test solutions for digital microfluidic biochips
IEEE Transactions on Circuits and Systems Part I: Regular Papers
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
A contamination aware droplet routing algorithm for the synthesis of digital microfluidic biochips
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Digital microfluidic biochips: recent research and emerging challenges
CODES+ISSS '11 Proceedings of the seventh IEEE/ACM/IFIP international conference on Hardware/software codesign and system synthesis
Digital microfluidic biochips: a vision for functional diversity and more than Moore
Proceedings of the International Conference on Computer-Aided Design
Integrated fluidic-chip co-design methodology for digital microfluidic biochips
Proceedings of the 2012 ACM international symposium on International Symposium on Physical Design
A high-performance online assay interpreter for digital microfluidic biochips
Proceedings of the great lakes symposium on VLSI
Fast online synthesis of generally programmable digital microfluidic biochips
Proceedings of the eighth IEEE/ACM/IFIP international conference on Hardware/software codesign and system synthesis
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Microfluidics-based biochips are soon expected to revolutionize clinical diagnosis, DNA sequencing, and other laboratory procedures involving molecular biology. Most microfluidic biochips today are based on the principle of continuous fluid flow and they rely on permanently etched microchannels, micropumps, and microvalves. We focus here on the automated design of “digital” droplet-based microfluidic biochips. In contrast to conventional continuous-flow systems, digital microfluidics offers dynamic reconfigurability; groups of cells in a microfluidics array can be reconfigured to change their functionality during the concurrent execution of a set of bioassays. We present a simulated annealing-based technique for module placement in such biochips. The placement procedure not only addresses chip area, but also considers fault tolerance, which allows a microfluidic module to be relocated elsewhere in the system when a single cell is detected to be faulty. Simulation results are presented for case studies involving the polymerase chain reaction and multiplexed in vitro clinical diagnostics.