Numerical computation of internal & external flows: fundamentals of numerical discretization
Numerical computation of internal & external flows: fundamentals of numerical discretization
Computer Methods in Applied Mechanics and Engineering
Analog Behavioral Modeling with the VERILOG-a Language
Analog Behavioral Modeling with the VERILOG-a Language
Modeling with an Analog Hardware Description Language
Modeling with an Analog Hardware Description Language
Automated Generation of Compact Models for Fluidic Microsystems
Analog Integrated Circuits and Signal Processing
Fault Modeling and Fault Simulation in Mixed Micro-Fluidic Microelectronic Systems
Journal of Electronic Testing: Theory and Applications
Development of a MEMS Testing Methodology
Proceedings of the IEEE International Test Conference
Testable Design and Testing of Micro-Electro-Fluidic Arrays
VTS '03 Proceedings of the 21st IEEE VLSI Test Symposium
Analysis of Failure Sources in Surface-Micromachined MEMS
ITC '00 Proceedings of the 2000 IEEE International Test Conference
Evaluation of Placement Techniques for DNA Probe Array Layout
Proceedings of the 2003 IEEE/ACM international conference on Computer-aided design
Test Planning and Test Resource Optimization for Droplet-Based Microfluidic Systems
ETS '04 Proceedings of the European Test Symposium, Ninth IEEE
Proceedings of the conference on Design, Automation and Test in Europe - Volume 2
Design of Fault-Tolerant and Dynamically-Reconfigurable Microfluidic Biochips
Proceedings of the conference on Design, Automation and Test in Europe - Volume 2
Unified high-level synthesis and module placement for defect-tolerant microfluidic biochips
Proceedings of the 42nd annual Design Automation Conference
Defect Tolerance for Gracefully-Degradable Microfluidics-Based Biochips
VTS '05 Proceedings of the 23rd IEEE Symposium on VLSI Test
Architectural-level synthesis of digital microfluidics-based biochips
Proceedings of the 2004 IEEE/ACM International conference on Computer-aided design
Concurrent Testing of Droplet-Based Microfluidic Systems for Multiplexed Biomedical Assays
ITC '04 Proceedings of the International Test Conference on International Test Conference
Composable Behavioral Models and Schematic-Based Simulation of Electrokinetic Lab-on-a-Chip Systems
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
CODES+ISSS '06 Proceedings of the 4th international conference on Hardware/software codesign and system synthesis
Computer-Aided Design and Test for Digital Microfluidics
IEEE Design & Test
ACM Journal on Emerging Technologies in Computing Systems (JETC)
Tabu search-based synthesis of dynamically reconfigurable digital microfluidic biochips
CASES '09 Proceedings of the 2009 international conference on Compilers, architecture, and synthesis for embedded systems
ACM Journal on Emerging Technologies in Computing Systems (JETC)
Computer-aided design for microfluidic chips based on multilayer soft lithography
ICCD'09 Proceedings of the 2009 IEEE international conference on Computer design
Routing-based synthesis of digital microfluidic biochips
CASES '10 Proceedings of the 2010 international conference on Compilers, architectures and synthesis for embedded systems
System-level modeling and synthesis of flow-based microfluidic biochips
CASES '11 Proceedings of the 14th international conference on Compilers, architectures and synthesis for embedded systems
Module-Based Synthesis of Digital Microfluidic Biochips with Droplet-Aware Operation Execution
ACM Journal on Emerging Technologies in Computing Systems (JETC)
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Advances in microfluidics technology offer exciting possibilities in the realm of enzymatic analysis, DNA analysis, proteomic analysis involving proteins and peptides, immunoassays, implantable drug delivery devices, and environmental toxicity monitoring. Microfluidics-based biochips are therefore gaining popularity for clinical diagnostics and other laboratory procedures involving molecular biology. As more bioassays are executed concurrently on a biochip, system integration and design complexity are expected to increase dramatically. This paper presents different actuation mechanisms for microfluidics-based biochips, as well as associated design automation trends and challenges. The underlying physical principles of eletrokinetics, electrohydrodynamics, and thermo-capillarity are discussed. Next, the paper presents an overview of an integrated system-level design methodology that attempts to address key issues in the modeling, simulation, synthesis, testing and reconfiguration of digital microfluidics-based biochips. The top-down design automation will facilitate the integration of fluidic components with microelectronic component in next-generation system-on-chip designs.