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The paper provides an overview of our research being performed in the area of interfaces for e-learning, with the emphasis on application of intelligent methods. We especially address the efforts being done in providing a suitable interaction for a class of intelligent e-learning systems --- Intelligent Tutoring Systems (ITSs), within the research framework of our home institutions. The specific issues being thus studied include adaptivity topics related to knowledge representation, interaction style as well as mobility support, along with related usability assessment methods. The dependence on intelligent handling of the former stems from the expected more efficient and effective solution of problems related to the diversity of users of Information and Communication Technology (ICT) supported education. In this respect we also shortly tackle and comment on a number of adaptable and adaptive interfaces for e-learning, which are in this context being conceptualized, implemented, and assessed both in vitro and in vivo .